For people suffering from Orthostatic Intolerance, Postural Orthostatic Tachycardia, Mast Cell Activtation or EDS. Follow me as I document my struggle towards better health.

B2 Migraines

Vitamin B2 Helping Migraines!
In my quest to find relief for symptoms of postural orthostatic tachycardia and orthostatic intolerance which DON'T include medications I thought I should share one particular treatment which has done wonders for me.  About a year and a half ago, I was visiting my very supportive neurologist about my migraines.  These migraines can occur any time of day and include symptoms such as:
  • black spots
  • blurry vision
  • white or grey outs
  • pain
  • spike driven into head pain
  • mind fog
  • numbness done left side of face and neck
  • slurring speech
  • staggering walk (or lurching as my family fondly describes it)
My neurologist knows I do not like to take medications as I believe they can further complicate an already complicated and not well understood set of bodily conditions.  He referred me to a 1998 study which showed that daily doses of 400mg of vitamin B2 or Riboflavin proved to significantly relieve migraine suffering in a small control group of patients.

Here is an excerpt from another research paper by Marecelo Bigal et al, which further discusses the link between migraines and B2:




A mitochondrial dysfunction resulting in impairment of oxygen metabolism and low cellular energy levels may play a role in migraine pathogenesis7. Riboflavin (vitamin B2) is the precursor of flavin mononucleotide and flavin adenine dinucleotide, which are required for the activity of flavoenzymes involved in the electron transport chain in the mitochondria of the cells9. Given to patients with mitochondriopathies, riboflavin improved some clinical and biochemical parameters10.





A double blind study of large doses of riboflavin (400 mg / day) compared with placebo in migraine prevention showed that riboflavin was significantly superior at reducing the attack frequency, headache intensity and other indexes after three months of therapy. The proportion of patients that improved at least 50% was 15% for placebo and 59% for riboflavin. No serious adverse events were reported11.


I can't comment on the science above but what I CAN say is that taking 200mg of vitamin B2 twice a day has SIGNIFICANTLY reduced the frequency and severity of my migraines.  How do I know it is the B2 that has reduced the migraines?  I know because when I stop taking the B2 after 4-5 days they come back.